We are bitterly upset at what has happened.

　　我們對發(fā)生的事感到極其難過。

　　Jack will have been very upset by all this.

　　這一切肯定會讓杰克非常難過。

　　It is little wonder (that) she was so upset.

　　她如此心煩意亂，并不奇怪。